Chronic Fluoride Ingestion Decreases 45Ca Uptake by Rat Kidney Membranes
نویسندگان
چکیده
منابع مشابه
Nutrient Interactions and Toxicity Chronic Fluoride Ingestion Decreases Ca Uptake by Rat Kidney Membranes
High exposures to fluoride (F) may occur in environments rich in F from natural or industrial sources and from misuse of F-containing dental care products, particularly by children. Both acute and chronic exposures to elevated levels of F have negative effects on several calcium-dependent processes, including kidney glomerular and tubular function. We examined the effect of chronic F ingestion ...
متن کاملCalcium uptake by rat kidney mitochondria.
t, 2 X 10-3. n2 Therefore the condition for convergence of the perturbation series is by no means fulfilled, and in order to get a valid approximation, one would have to solve the secular equation. which would lead to nonlocalized states. Further work in this direction is in progress. The above considerations hold also for more extensive systems. It seems possible that they can be applied to bi...
متن کاملUptake and release of 45Ca by Myxicola axoplasm
The binding and release of 45Ca by axoplasm isolated from Myxicola giant axons were examined. Two distinct components of binding were observed, one requiring ATP and one not requiring ATP. The ATP-dependent binding was largely prevented by the addition of mitochondrial inhibitors, whereas the ATP-independent component was unaffected by these inhibitors. The ATP-independent binding accounted for...
متن کاملDna Damage Induced by Fluoride in Rat Kidney Cells
DNA damage by fluoride to newborn rat kidney cells isolated by enzymic digestion is reported. The cells were exposed for 24 hr to sodium fluoride at NaF concentrations of 0, 0.2, 0.4, 0.8, and 1.0 mM. Damage to DNA was determined by single cell gel electrophoresis assay (Comet assay). Significant breakage of DNA strands occurred at 0.8 mM NaF and above. Compared with the control group, the come...
متن کاملEffect of verapamil on 45Ca uptake by synaptosomes.
The effect of verapamil on K-stimulated 45Ca uptake (the difference between uptake in 60 mM-Ko medium and 5 mM-Ko medium) was studied using a synaptosomal fraction from rat brain. Verapamil inhibited K-stimulated 45Ca uptake, but not 45Ca uptake in 5 mM-Ko media (1 mM- and 0.1 mM-Cao media). The concentrations of verapamil inducing 50% inhibition of K-stimulated 45Ca uptake (ID50) in 1 mM- and ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 1999
ISSN: 0022-3166,1541-6100
DOI: 10.1093/jn/129.6.1209